Organic fertilizer is a major limiting factor in crop production, especially for vegetables during the winter season in Bangladesh. Recently, an experiment was conducted at ARS, BARI, Satkhira on three types of organic fertilizer (OF) like OF from Co-compost (Faecal Sludge and Municipal Solid Waste), OF from earthworm compost (Vermicompost) and OF from cowdung whereas chemical fertilizer were applied as control treatment. Now a day’s farmers are cultivating tomato in saline areas and normally they do not use any compost fertilizers at their field as an organic fertilizer, therefore, it is urgent to find out the suitable combining dose of different types of compost and chemical fertilizers for maximizing the yield or know the best combination of chemical and organic fertilizer as well as the economic benefit from best treatment considering soil health. For this reason, this experiment was conducted in RCBD design with three dispersed replications in the winter season 2016-17 at ARS, Satkhira. Four fertilizer doses viz., T1 = 100% Chemical Fertilizer (Soil Test Based, FRG, 2012), T2 = Co-compost @ 2 t ha-1 with 50% recommended dose of chemical fertilizer (RDF), T3 = Vermicompost @ 2 t ha-1 with 50% RDF, T4= Cowdung @ 5 t ha-1; were set as the treatments. Tomato (BARI Tomato-14) was planted on 15 November 2016; during final land preparation following proper methodology. Only four irrigations were applied after 10, 25 and 35 and 45 days after plantation. It was found that treatment T2 gave the highest yield (45.94 t ha-1) followed by T3 (42.16 t ha-1), T1 (32.50 t ha-1) and T4 (32.50 t ha-1). From the economic study, it was found that higher income obtained from using co-compost along with chemical fertilizer (198825 Tk. ha-1) followed by T3 (155025 Tk. ha-1), T1 (118025 Tk. ha-1) and T4 (190575 Tk. ha-1). Now, it is clear that 2 ton co-compost with 50% inorganic fertilizer from Recommended Dose of Fertilizer (RDF) gave the highest yield with economic benefit. Also soil salinity was recorded minimum in co-compost treated plot.