The present study was conducted to find out the effect of analgesic and anaesthetic drugs for caudal epidural analgesia in Black Bengal goats. A series of thirty two (32) analgesic trails were conducted in goats age ranged from 8 to 12 months and with an average body weight of 8.1 kg. The animals were divided into four groups (n=4) and a replication of 8 trails was performed in each group at least one week interval. Two percent (2%) lidocaine hydrochloride (4 mg kg-1), 2% lidocaine hydrochloride with adrenaline (4 mg kg-1), 0.5% bupivacaine hydrochloride (1.0 mg kg-1) and ketamine hydrochloride (4 mg kg-1) were used to perform caudal epidural analgesia. The time of onset of anaesthesia, peak time of anaesthesia, area of desensitization and duration of anaesthesia were observed. 2% Lidocaine hydrochloride showed rapid onset of analgesia. 0.5% bupivacaine hydrochloride produced the highest area of desensitization in thigh region during caudal epidural analgesia. Perineal region and tail were totally desensitized during epidural analgesia. 0.5% bupivacaine hydrochloride prolonged the duration of analgesia during epidural analgesia. 2% Lidocaine hydrochloride and 2% Lidocaine hydrochloride with adrenaline showed no side effects whereas 0.5% bupivacaine hydrochloride showed shivering and drowsiness, ketamine hydrochloride excitement and drowsiness. It seemed that 2% Lidocaine hydrochloride is more effective whereas 0.5% bupivacaine hydrochloride is associated with side effects. Though ketamine hydrochloride is a dissociative agent, it could also be used in epidural analgesia.